Language

CAS No.119141-88-7 | Esomeprazole

Name: Esomeprazole CAS No. 119141-88-7 MF:C17H19N3O3S MW:345.42 Purity:98% Package: 10g,25g,50g,100g,250g Worldwide Delivery

Categories：

Other Life Science Chemicals

Email：sale06@alfachem.cn

Inquiry

Chat Now

Product introduction

Introduction and application of CAS No. 119141-88-7 | Esomeprazole

Synonyms:

EsoMaprozole;

1H-BenziMidazole,6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-;

EsoMeprazoleECPellets8.5%;

6-Methoxy-2-{(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl}-1H-benziMidazole;

Esomeprazole(Na,Mg);

(5-methoxy-1H-benzimidazol-2-yl)[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfoniumolate;

(S)-Esomeprazole

Specification:

ITEMS	SPECIFICATION
CAS	119141-88-7
MF	C17H19N3O3S
MW	345.42
Specific rotation	D20 -155° (c = 0.5 in chloroform)
Boiling point	600.0±60.0 °C
Density	1.37±0.1 g/cm3
Acidity coefficient	8.50±0.10
Solubility	DMF: 30 mg/ml, DMSO: 20 mg/ml, ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml
Form	Solid
Storage condition	Sealed in dry,Room Temperature

Overview:

Esomeprazole (English Inexium), also known as esomeprazole, esomeprazole, esotoprazole, esomeprazole magnesium, levomeprazole, is the derivative of omeprazole S-isomer.

Physical and chemical properties:

Esomeprazole (S) Omeprazole has a molecular weight of 345.41600, a density of 1.37g/cm3, a boiling point of 600ºCat760mmHg, a flash point of 316.7ºC, a refractive index of 1.669, and a vapor pressure of 0mmHgat25°C. , a white or off-white freeze-dried block or powder. It can effectively inhibit gastric acid secretion and is often used to treat diseases related to gastric acid secretion disorders.

Indications：

1. Gastroesophageal reflux disease (GERD) Gastroesophageal reflux disease (GERD) is caused by the reflux of gastric contents into the esophagus, causing symptoms such as heartburn, acid reflux, and retrosternal pain, and causing pathological damage to the esophageal mucosa. It is a clinical One of the common acid-related diseases, suppressing gastric acid is the key to the treatment of gastroesophageal reflux disease. Esomeprazole is the levorotatory isomer of omeprazole (Nexium). It has a rapid onset of action and good acid-suppressing effect. It is used to treat reflux esophagitis alone or in combination with gastrointestinal prokinetic drugs. Or digestive tract mucosal protective agent, the efficacy is better than other PPIs (esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole), for the treatment of reflux esophagitis in the elderly and children Safe and effective for reflux esophagitis.

2. Treatment of erosive reflux esophagitis

3. Long-term maintenance treatment to prevent recurrence of cured esophagitis patients

4. Symptom control of gastroesophageal reflux disease (GERD) combined with appropriate antimicrobial therapy to eradicate Helicobacter pylori

5. Heal duodenal ulcers associated with Helicobacter pylori infection

6. Prevent the recurrence of peptic ulcers associated with Helicobacter pylori

Package and transportation :

Package: 10g,25g,50g,100g,250g